PUSHING THE BOUNDARIES of Peptide and oligonucleotide purification

In peptide API manufacturing, robust purification processes are essential for attaining high purity and yield. These processes are also critical determinants of cost efficiency and overall process productivity.

Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) has shown to achieve substantially higher capacity and yield than single-column batch processes. This innovative purification process leads to time savings, economic advantages and a lower environmental footprint.

Key Highlights:

• Efficiency and Sustainability: MCSGP technology revolutionizes purification making it a game-changer in sustainable manufacturing. MCSGP reduces solvent consumption by an impressive 71%, making it a greener choice for large-scale manufacturing.
• Automation and Productivity: Operating 24/7, MCSGP’s fully automated system eliminate extra purification steps and significantly enhancing productivity.
• Economic and Environmental Impact: This innovative process not only reduces raw material costs and process mass intensity (PMI) but also supports environmental sustainability by minimizing the purification process’s footprint.

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